University of Leeds

University of Leeds

Ion Channels, Transporters, Receptors and Enzymes

Research is ongoing into the structure, function relationships, regulation, trafficking and targeting of membrane proteins in organisms ranging from bacteria to plants and mammals, both in health and disease; key classes of channels investigated include voltage and ligand gated potassium channels, chloride channels, water channels, p2x purinergic receptors and TRP channels; in the transporter area, a wide diversity of protein families are under study, including cation linked metabolite and drug transporters, cation exchangers, abc transporters and rotary atpase complexes, while investigations on receptors include GPCR's and 2-component systems; studies of membrane bound enzymes include electron-transport chains (etc) including photosystems and various quionone-converting enzymes such as bacterial terminal oxidases; in addition to investigations of function, there is a focus on determination of the structures of membrane transporters, ion channels and membrane protein complexes by EM and x-ray crystallography, together with the design and synthesis of selective ligands.

Entry requirements

A Bachelor's degree with a 2.1 or above in a relevant subject; applicants with a 2.2 and a Master's degree at merit or higher will also be eligible. GCSE English language grade C (or above) or an equivalent recognised English language qualification e.g. IELTS: 6.5 with not less than 6.0 in listening, reading, speaking and writing.

Qualifications

Qualification Study mode Start month Fee Course duration
PhD Full-time - 3 years

Campus details

Campus name Town Postcode Region Main campus Campus Partner
University of Leeds Leeds LS2 9JT Yorkshire and the Humber

Get in touch

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Key information

Contact: 
Biological Sciences - Research Postgraduate
Telephone number: 
0113 343 8186