University of Leeds
Ion Channels, Transporters, Receptors and Enzymes
Research is ongoing into the structure, function relationships, regulation, trafficking and targeting of membrane proteins in organisms ranging from bacteria to plants and mammals, both in health and disease; key classes of channels investigated include voltage and ligand gated potassium channels, chloride channels, water channels, p2x purinergic receptors and TRP channels; in the transporter area, a wide diversity of protein families are under study, including cation linked metabolite and drug transporters, cation exchangers, abc transporters and rotary atpase complexes, while investigations on receptors include GPCR's and 2-component systems; studies of membrane bound enzymes include electron-transport chains (etc) including photosystems and various quionone-converting enzymes such as bacterial terminal oxidases; in addition to investigations of function, there is a focus on determination of the structures of membrane transporters, ion channels and membrane protein complexes by EM and x-ray crystallography, together with the design and synthesis of selective ligands.
|Qualification||Study mode||Start month||Fee||Course duration|
|Campus name||Town||Postcode||Region||Main campus||Campus||Partner|
|University of Leeds||Leeds||LS2 9JT||Yorkshire and the Humber|
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Biological Sciences - Research Postgraduate
0113 343 8186